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Determination of Absolute Content of Cyetpyrafen by qNMR Analysis

Date: May 5,2022 |Hits: 1111 Download PDF How to cite this paper

Jie Lang, Huibin Yang, Haibo Yu*

State Key Laboratory of the Discovery and Development of Novel Pesticides, Shenyang Sinochem Agrochemicals R&D Co., Ltd., Shenyang 110021, Liaoning, China.

*Corresponding author: Haibo Yu


This paper established a rapid, simple method for determination of absolute content of cyetpyrafen by qNMR. 1H NMR spectra was acquired with deuterodimethyl sulfoxide (DMSO-D6) as the solvent and hydroquinone as internal reference standard under the conditions of temperature 25℃, pulse angle 90°, pulses width 8.0 μs, relaxation delay 30 s, and scans 8. The proton peaks of cyetpyrafen (δ=6.35) and hydroquinone (δ=6.55) were taken as quantitative peaks. The peak area ratio y (As/Ar) and concentration ratio x (Cs/Cr) were linearly regressed, and the correlation coefficient was 0.9999. The RSD value of repeatability test was 0.80%, and the RSD value of stability test was 0.54%. The content of cyetpyrafen was determined as 99.8%. The result shows that qNMR can be used for quantitative determination of cyetpyrafen without reference standard, which is rapid, accurate and simple.


[1] Dusengem, S. L. and Zhang, J. Y. (2017). Advance on Method for Determination of Imidacloprid Pesticides Residues in vegetables. The Journal of the Science of Food and Agriculture, 1(1), 1-3.

[2] Bin Li, Haibo Yu, Yanmei Luo, et al. (2016). The Synthesis and Acaricidal Activity of SYP-9625. Modern Agrochemicals, 2016, 15(06): 15-16, 20.

[3] Jingyu Sun, Chunji Li, Jinqi Jiang, et al. (2022). Cross resistance, inheritance and fitness advantage of cyetpyrafen resistance in two-spotted spider mite, Tetranychus urticae. Pesticide Biochemistry and Physiology, 2022,105062. ISSN 0048-3575.

[4] Yanming Ye. (2017). Analysis of SYP-9625 TC by HPLC. Agrochemicals, 2017, 56(6): 424-426.

[5] Simmler, C., Napolitano, J. G., McAlpine, J. B., et al. (2014). Universal quantitative NMR analysis of complex natural samples. Current Opinion in Biotechnology, 2014, 25: 51-59.

[6] Gökhan DİKMEN, Okan USLU, et al. (2021). The application of qNMR for the determination of rosuvastatin in tablet form. Turkish Journal of Chemistry, (2021)45: 132-142.

[7] Chinese Pharmacopoeia Commission. (2015). Pharmacopoeia of the People’s Republic of China. Beijing China Medical Science Press, 2015: 52.

How to cite this paper

Determination of Absolute Content of Cyetpyrafen by qNMR Analysis

How to cite this paper: Jie Lang, Huibin Yang, Haibo Yu. (2022) Determination of Absolute Content of Cyetpyrafen by qNMR Analysis. International Journal of Food Science and Agriculture6(2), 149-153.

DOI: http://dx.doi.org/10.26855/ijfsa.2022.06.003

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