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A New Scientific Paradigm of Reverse Vaccinology: An Annotation

Date: August 27,2021 |Hits: 489 Download PDF How to cite this paper

Abu S. M. Giasuddin1,*, Khadija A. Jhuma1, Waziul A. Chowdhury1, Rubayat S. Giasuddin2

1Impulse Hospital, ImHS&RCLtd, 304/E Tejgaon Industrial Area, Dhaka-1208, Bangladesh.

2Department of Medicine, Anwer Khan Modern Medical College, Road No. 8A, Dhanmondi, Dhaka-1207, Bangladesh.

*Corresponding author: Abu S. M. Giasuddin


Since the pioneer work in 1796 by Edward Jenner, Father of Vaccination, many vaccines against infectious diseases have become routinely available saving lives in the community all over the world. The modern terminology of ‘Vaccination’ was derived from ‘Vacca’ meaning cow. Renowned biomedical scientists contributed in the development of ‘Immunology’ as an important biomedical science. Many of them have received ‘Nobel Prize’ for their noble discoveries in Immunology. The development of nucleic acid sequencing technology has changed the landscape of the evolving field of vaccinology since 1990s. The methodology of Reverse Vaccinology, application of genomic technologies in vaccine research, represented a major revolution in the process of discovering novel vaccines. Bringing a new vaccine from basic research to a product ready for commercial and community use is a very challenging task that requires formulating completely new scientific paradigm. Reverse Vaccinology is a good and classical example of such a paradigm. In fact, it is having, and will have, tremendous applications and implications in the development of protective vaccines particularly against the pandemic ‘COVID-19’ caused by ‘SARS-CoV-2’ creating havoc all over the world presently.


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How to cite this paper

A New Scientific Paradigm of Reverse Vaccinology: An Annotation

How to cite this paper: Abu S. M. Giasuddin, Khadija A. Jhuma, Waziul A. Chowdhury, Rubayat S. Giasuddin. (2021) A New Scientific Paradigm of Reverse Vaccinology: An Annotation. International Journal of Clinical and Experimental Medicine Research5(4), 431-434.

DOI: http://dx.doi.org/10.26855/ijcemr.2021.10.002

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