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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2026.05.016

Risk Factors and Prevention Strategies of Perioperative Myocardial Injury in Elderly Patients with Complex Coronary Artery Lesions Undergoing Interventional Therapy

Hongchang Luo

Liuzhou Worker's Hospital, Liuzhou 545500, Guangxi, China.

*Corresponding author: Hongchang Luo

Published: May 30,2026

Abstract

The incidence and clinical risks of perioperative myocardial injury are high in elderly patients with complex coronary artery lesions receiving interventional therapy. This paper analyzes the core risk factors from three dimensions: patients’ basic conditions, coronary lesion characteristics, and surgical operations, and elaborates the internal pathogenesis, including microcirculation disturbance, ischemia-reperfusion injury, inflammatory response, and oxidative stress. A full-process management system covering precise preoperative evaluation and pretreatment, standardized intraoperative operation and microcirculation protection, as well as close postoperative monitoring and complication intervention, was established, which is implemented through multidisciplinary whole-course nursing. In accordance with the latest guidelines and consensus, individualized medication regimens, surgical schemes, and rehabilitation plans were optimized. This study provides clinical references for preventing perioperative myocardial injury and improving the efficacy of interventional therapy in elderly patients.

Keywords

Elderly patients; complex coronary artery lesions; interventional therapy; perioperative myocardial injury; prevention and control strategies

References

[1] Ye HY, Cui SM, Han ZJ, et al. Effect of macrophage infiltration based on optical coherence tomography on perioperative myocardial injury in patients undergoing elective percutaneous coronary intervention. Chin J Interv Cardiol. 2026;34(3):128-38.

[2] Guo WH, Song YC, Deng LH, et al. Effect of Xuefu Zhuyu Decoction combined with electroacupuncture at Neiguan point on reperfusion injury after PCI in patients with acute myocardial infarction. Glob Tradit Chin Med. 2026;19(1):158-62.

[3] Zhou HL, Jing XG, Kong SY. Diagnostic value of dynamic electrocardiogram parameters combined with serum myocardial injury markers in asymptomatic myocardial ischemia of coronary heart disease. J Clin Electrocardiol. 2025;34(6):445-9.

[4] Ye YZ, Pan RQ, Su XR. Application effect of intracoronary versus intravenous tirofiban in patients with acute myocardial infarction undergoing PCI. Chin Community Dr. 2025;41(35):10-2.

[5] Aji M, Yilhamu Z, Xie YH, et al. Construction of risk prediction model for postoperative myocardial injury after direct PCI in patients with acute coronary syndrome. J Diffic Dis. 2025;24(12):1418-23.

[6] Guo LH, Zhang JC, Liang ZX, et al. Efficacy of different coronary blood flow isolation techniques in off-pump coronary artery bypass grafting. Natl Med J China. 2025;105(44):4076-80.

[7] Luo JH, Zhong HY, Xie XW, et al. Correlation analysis of blood pressure variability, heart rate variability with coronary micro-vascular dysfunction and myocardial injury markers. Prog Mod Biomed. 2025;25(22):3546-54.

[8] Xia YF, Wang S. Research progress of NLRP3 inflammasome signaling pathway and postoperative myocardial injury after PCI in patients with coronary heart disease. China Med Herald. 2025;22(32):165-70.

[9] Zhang YW, Xiong QQ, Deng Y. Effect of Shensong Yangxin Capsules combined with nicorandil on myocardial injury and plate-let function after PCI in patients with acute coronary syndrome. China Contemp Med. 2025;32(30):53-6,61.

Copyright

© 2026 by the author(s).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND) license, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not modified or adapted.
https://creativecommons.org/licenses/by-nc-nd/4.0/

How to cite this paper

Risk Factors and Prevention Strategies of Perioperative Myocardial Injury in Elderly Patients with Complex Coronary Artery Lesions Undergoing Interventional Therapy

How to cite this paper: Hongchang Luo. (2026) Risk Factors and Prevention Strategies of Perioperative Myocardial Injury in Elderly Patients with Complex Coronary Artery Lesions Undergoing Interventional Therapy. International Journal of Clinical and Experimental Medicine Research10(3), 245-249.

DOI: http://dx.doi.org/10.26855/ijcemr.2026.05.016