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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2026.05.004

The First Comprehensive Report from Mardin, Turkey: Antimicrobial Resistance Profiles of Microorganisms Isolated from Blood Cultures in Mardin Training and Research Hospital

Kenan Arda1,2, Halit Irmak3, Abdurrahman Dündar4,*

1Department of Biology, Postgraduate Education Institute, Mardin Artuklu University, Mardin 47000, Turkey.

2Department of Medical Microbiology, Central Laboratory Unit, Mardin Training and Research Hospital, Mardin 47000, Turkey.

3Department of Computer Engineering, Faculty of Engineering and Architecture, Mardin Artuklu University, Mardin 47000, Turkey.

4Medical Documentation and Secretarial Program, Department of Medical Services and Techniques, Vocational School of Health Services, Mardin Artuklu University, Mardin 47000, Turkey.

*Corresponding author: Abdurrahman Dündar

Published: May 6,2026

Abstract

Background: Mardin province has the highest antibiotic consumption rate in Turkey, yet no comprehensive antimicrobial resistance data exist for bloodstream isolates from this region. This study provides the first report on resistance profiles of microorganisms isolated from blood cultures at Mardin Training and Research Hospital. Methods: Blood culture results from 4790 patients (May 2024-May 2025) were retrospectively analyzed. Antimicrobial susceptibility testing was performed. Resistance rates were compared between ICU and non-ICU settings. Results: Of 3301 isolates, 67.8% were Gram-positive and 32.2% Gram-negative. Acinetobacter baumannii showed 100% carbapenem resistance; colistin remained effective. Klebsiella pneumoniae had 69.4% meropenem resistance (73.2% in ICU vs. 33.3% in non-ICU). Clindamycin resistance in Staphylococcus epidermidis differed markedly (67.6% in ICU vs. 0% in non-ICU). Conclusion: Alarmingly high resistance rates, especially among ICU Gram-negative pathogens, necessitate urgent infection control measures and local surveillance-guided antibiotic stewardship.

Keywords

Bloodstream infections; intensive care unit (ICU); antimicrobial resistance; antibiotics; Gram-negative bacteria; Mardin

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How to cite this paper

The First Comprehensive Report from Mardin, Turkey: Antimicrobial Resistance Profiles of Microorganisms Isolated from Blood Cultures in Mardin Training and Research Hospital

How to cite this paper: Kenan Arda, Halit Irmak, Abdurrahman Dündar. (2026) The First Comprehensive Report from Mardin, Turkey: Antimicrobial Resistance Profiles of Microorganisms Isolated from Blood Cultures in Mardin Training and Research Hospital. International Journal of Clinical and Experimental Medicine Research10(3), 185-194.

DOI: http://dx.doi.org/10.26855/ijcemr.2026.05.004