Zihan Li1, Zhiyuan Wu1, Yiqing Huang2, Songwu Dong1,*
1Department of Cardiology, The People's Hospital of Bozhou, Bozhou 236800, Anhui, China.
2Oncology Department, The People's Hospital of Bozhou, Bozhou 236800, Anhui, China.
*Corresponding author: Songwu Dong
Abstract
Objective: To investigate the dynamic association between the index of microcir-culatory resistance (IMR) measured after percutaneous coronary intervention (PCI) and myocardial injury and inflammatory markers in patients with acute myocardial infarction (AMI). Methods: A total of 128 patients with AMI who underwent PCI at our hospital between January 2022 and December 2025 were retrospectively analyzed. According to the IMR value measured immediately after PCI, patients were divided into a high-IMR group (n = 52) and a low-IMR group (n = 76). Differences in myocardial injury markers and inflammatory indices between the two groups were compared at multiple time points before and after surgery. Pearson correlation analysis was performed to explore the correlation between IMR values and the above indicators. Results: At 6 h, 24 h, and 72 h after PCI, the levels of cardiac troponin I (cTnI) and creatine kinase-MB (CK-MB) in the high-IMR group were significantly higher than those in the low-IMR group (P < 0.05). At 7 days postoperatively, there was no significant difference in cTnI or CK-MB levels between the two groups (P > 0.05). At 6 h, 24 h, and 72 h after PCI, the levels of interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) in the high-IMR group were significantly higher than those in the low-IMR group (P < 0.05). Pearson correlation analysis showed that IMR values measured immediately after PCI were positively correlated with postoperative CK-MB, cTnI, hs-CRP, and IL-6 levels (P < 0.05). Conclusion: In patients with AMI, elevated IMR values after PCI are closely associated with more severe myocardial injury and a more pronounced inflammatory response.
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How to cite this paper
Dynamic Association Between the Index of Microcirculatory Resistance After PCI and Myocardial Injury and Inflammatory Markers in Patients with Acute Myocardial Infarction
How to cite this paper: Zihan Li, Zhiyuan Wu, Yiqing Huang, Songwu Dong. (2026) Dynamic Association Between the Index of Microcirculatory Resistance After PCI and Myocardial Injury and Inflammatory Markers in Patients with Acute Myocardial Infarction. International Journal of Clinical and Experimental Medicine Research, 10(2), 115-118.
DOI: http://dx.doi.org/10.26855/ijcemr.2026.03.010