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Advance in Immunology and Allergy Research

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ArticleOpen Access http://dx.doi.org/10.26855/aiar.2025.09.005

Analysis of Influence of Immunohistochemical Staining on Quality Control of Pathological Techniques

Chao Liu

Nanjing Pukou District Hospital of Traditional Chinese Medicine, Nanjing 211800, Jiangsu, China.

*Corresponding author: Chao Liu

Published: September 29, 2025

Abstract

Objective To analyze the effect of immunohistochemical staining on the quality control of pathological techniques. Methods A total of 96 patients who underwent pathological examination in our hospital from July 2022 to July 2023 were included in the study. All patients were randomly divided into random groups, 48 of which were assigned to the control group, and routine HE staining was performed on them. Another 48 cases were assigned to the observation group, and immunohistochemical staining was performed on them. The two groups were evaluated comprehensively from the quality of section, diagnosis and pathological examination. Results Compared with the control group, the section quality of the observation group had a more obvious trend of improvement, and the two groups had statistically significant significance (P < 0.05). Compared with the control group, the diagnosis rate of the observation group was more significantly increased, and there was statistically significant significance between the two groups (P < 0.05). Compared with the control group, the scores of sample quality, stain quality and reagent quality in the observation group were more significantly increased, with statistically significant significance between the two groups (P < 0.05). Conclusion Immunohistochemical staining in clinicopathological examination can greatly improve the quality of pathological techniques and ensure the diagnosis rate of diseases.

Keyword

Immunohistochemical staining; Pathological technique; Quality control

References

[1] Wang XB, Ju HY, Sun LY, et al. Analysis of the impact of immunohistochemical staining on the quality control of pathological technology. Guizhou Medicine. 2023;47(9):1461-1463.

[2] Luo FJ. Analysis of the impact of immunohistochemical staining on the quality control of pathological technology. Electronic Journal of Clinical Medical Literature. 2019;6(4):147.

[3] Zhao QL. Analysis of the impact of immunohistochemical staining on the quality control of pathological technology. Journal of General Stomatology. 2019;6(9):141.

[4] Wang LS, Che C, Li ZL, et al. Research on immunohistochemical pathology technology and quality control methods. China Medical Guide. 2019;17(4):151-152.

[5] Hua YY, Long AY, Wang Y. Analysis and countermeasures of quality control issues of immunohistochemical pathology technology. Electronic Journal of Clinical Medical Literature. 2020;7(22):132,169.

[6] Chai CQ. Study on the effect and value of special staining combined with immunohistochemistry in tumor pathological diagnosis. Chinese Journal of Health Care and Nutrition. 2023;33(1):130-132.

[7] Chen JJ, Zhang Y, Li MM, et al. Application experience of fully automatic immunohistochemistry instrument in standardized staining quality control. Journal of Clinical and Experimental Pathology. 2020;36(5):610-612.

[8] Zhang Y. Application value of immunohistochemistry quality control management in the pathological diagnosis of gastrointestinal tumors. China Medical Guide. 2023;21(4):93-95,127.

Copyright

© 2025 by the author(s).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND) license, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not modified or adapted.
https://creativecommons.org/licenses/by-nc-nd/4.0/

How to cite this paper

Analysis of Influence of Immunohistochemical Staining on Quality Control of Pathological Techniques

How to cite this paper: Chao Liu. (2025) Analysis of Influence of Immunohistochemical Staining on Quality Control of Pathological Techniques. Advance in Immunology and Allergy Research1(1), 18-21.

DOI: http://dx.doi.org/10.26855/aiar.2025.09.005