Xin Xia*, Haixia Ren
Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.
*Corresponding author: Xin Xia
Abstract
Objective: To investigate the impact of invisible aligners on oral cleanliness and gingival crevicular fluid inflammatory factors in patients undergoing orthodontic treatment. Methods: This study included 60 patients undergoing orthodontic treatment, all treated between June 2022 and June 2024. Patients were divided into a control group and an observation group (30 patients each) based on the type of orthodontic appliance used. The control group used fixed appliances, while the observation group used invisible aligners. Oral cleanliness [plaque index (PLI), debris index (DI)] and levels of gingival crevicular fluid inflammatory factors [tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1beta (IL-1β)] were compared between the two groups. Results: There was no significant difference in PLI and DI scores between the two groups before treatment (P > 0.05). After six months of treatment, both groups showed increased PLI and DI scores, but the observation group had lower scores than the control group (P < 0.05). There was no significant difference in TNF-α, IL-6, and IL-1β levels between the two groups before treatment (P > 0.05). After six months of treatment, both groups showed increased levels of these inflammatory factors, but the observation group had lower levels than the control group (P < 0.05). Conclusion: Using invisible aligners for orthodontic treatment helps maintain oral cleanliness and reduces levels of gingival crevicular fluid inflammatory factors.
References
[1] Chang J, Li X. Multivariate analysis of oral mucosal ulcers during orthodontic treatment. World J Clin Cases. 2024;12(26):5868-76.
[2] Zeng X, Chen X, Huang X. Comparative study on the effect of invisible aligners and traditional fixed appliances on alveolar bone remodeling in patients with severe periodontitis orthodontics. J Cent South Med Sci. 2024;52(5):811-4.
[3] Luo X, Liu Y. Impact of bracketless invisible aligners and fixed appliances on oral microbial flora and gingival crevicular fluid sICAM-1, MMP-8 levels in orthodontic treatment patients. J Clin Exp Med. 2024;23(20):2219-23.
[4] Kandil A, Al Kordy SA, Boghdady DE, et al. Evaluation of SARDAC technique during en-masse retraction in lingual orthodontics. Semin Orthod. 2023;29(1):90-100.
[5] Punzalan P, Al Talib T, Fusco A, et al. Effect of dietary components on the shear bond strength of orthodontics brackets after thermal aging. Open J Stomatol. 2024;14(6):309-15.
[6] Zhou R, Li J, Sun F. The impact of orthodontic aligners without brackets on periodontal indices and aesthetic appearance in orthodontic patients. Chin Med Aesthet. 2024;14(9):69-71.
[7] Zhang X. Comparison of self-ligating brackets and orthodontic aligners on pain and discomfort in orthodontic patients. Pract Integr Tradit Chin West Med. 2024;24(12):90-2,103.
[8] Gao H, Liu J, Wang H, et al. Clinical observation of orthodontic aligners without brackets on periodontal disease patients. Beijing Med J. 2023;45(5):427-31.
[9] Gan M, Wu A, Chen X. Comparison of orthodontic aligners without brackets and fixed appliances on gingival crevicular fluid inflammatory indicators and oxidative stress indicators in orthodontic treatment patients. Grassroots Med Forum. 2024;28(32):11-4.
[10] Xie W. The effect of orthodontic aligners without brackets and traditional fixed orthodontic techniques on gingival crevicular fluid inflammatory status and dental pulp vitality in orthodontic patients. Mod Diagn Treat. 2022;33(19):2908-10.
How to cite this paper
The Impact of Invisible Aligners on Oral Cleanliness and Inflammatory Factors in Gingival Crevicular Fluid of Orthodontic Patients
How to cite this paper: Xin Xia, Haixia Ren. (2025) The Impact of Invisible Aligners on Oral Cleanliness and Inflammatory Factors in Gingival Crevicular Fluid of Orthodontic Patients. International Journal of Clinical and Experimental Medicine Research, 9(3), 339-342.
DOI: http://dx.doi.org/10.26855/ijcemr.2025.05.016