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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2024.07.008

Eosinophilic Gastroenteritis Complicated with Intestinal Obstruction: A Case Report

Min Li

Department of Gastroenterology, The First Hospital Affiliated to Hunan Normal University (Hunan Provincial People's Hospital), Changsha 410000, Hunan, China.

*Corresponding author: Min Li

Published: August 16,2024

Abstract

Eosinophilic gastroenteritis (EGE) is a rare digestive tract disease characterized by eosinophilic infiltration of gastrointestinal tissues. The stomach and small intestine are the most commonly affected areas. The most common symptoms are abdominal pain, diarrhea, nausea, and vomiting, which are non-specific gastrointestinal symptoms, so they are easy to be misdiagnosed or missed. Although several effective treatment options for EGE have been proposed and demonstrated, such as dietary interventions, corticosteroids, and surgery, the pathogenesis of the disease is still unclear. A case of eosinophilic enteritis is reported as follows. In this paper, a case of eosinophilic gastroenteritis was taken as the research object, and the related literature was reviewed to understand the pathogenesis, clinical characteristics, diagnosis, and treatment of eosinophilic enteritis, to improve the understanding of clinicians on the disease and reduce misdiagnosis and missed diagnosis. For future treatment studies of eosinophilic gastroenteritis, trade-offs should be made between the efficacy and safety of different treatment modalities, and prognosis should be evaluated.

Keywords

Eosinophilic Gastroenteritis; intestinal obstruction; ileus

References

[1] Ingle SB, Hinge Ingle CR. Eosinophilic gastroenteritis: An unusual type of gastroenteritis. World J Gastroenterol. 2013; 19:5

[2] Heikh RA, Prindiville TP, Pecha RE, Ruebner BH. Unusual presentations of eosinophilic gastroenteritis: case series and review of literature. World J Gastroenterol. 2009; 15(17):2156-2161.

[3] Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis. Medicine (Baltimore). 1970; 49(4):299-319.

[4] Rothenberg ME, Hottinger SKB, Gonsalves N, Furuta GT, Collins MH, Talley NJ, et al. Impressions and aspirations from the FDA GREAT VI workshop on eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis and perspectives for progress in the field. J Allergy Clin Immunol. 2022; 149:844-853. 

[5] Chen MJ, Chu CH, Lin SC, Shih SC, Wang TE. Eosinophilic gastroenteritis: clinical experience with 15 patients. World Gastroenterol. 2003; 9(12):2813-2816.

[6] Tian XQ, Chen X, Chen SL. Eosinophilic gastroenteritis with abdominal pain and ascites: a case report. World J Clin Cases. 2021, 9(17): 4238-4243. 

[7] Sunkara T, Rawla P, Yarlagadda KS, Gaduputi V. Eosinophilic gastroenteritis: diagnosis and clinical perspectives. Clin Exp Gastroenterol. 2019; 12:239-53.

[8] Egan M, Furuta GT. Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018; 121: 162-167.

[9] Katz A.J., Twarog F.J., Zeiger R.S., Falchuk Z.M. Milk-sensitive and eosinophilic gastroenteropathy: similar clinical features with contrasting mechanisms and clinical course. J. Allergy Clin. Immunol. 1984, 74 (1) : 72-78.

[10] Chang JY, Choung RS, Lee RM, Locke GR, Schleck CD, Zinsmeister AR, et al. A shift in the clinical spectrum of eosino-philic gastroenteritis toward the mucosal disease type. Clin Gastroenterol Hepatol. 2010;8(8):669-75.

[11] Friesen CA, Neilan NA, Schurman JV, Taylor DL, Kearns GL, Abdel-Rahman SM. Montelukast in the treatment of duodenal eosinophilia in children with dyspepsia: Effect on eosinophil density and activation in relation to pharmacokinetics. BMC Gastroenterol. 2009; 9:32.

[12] Netzer P, Gschossmann JM, Straumann A, Sendensky A, Weimann R, Schoepfer AM. Corticosteroid-dependent eosinophilic oesophagitis: Azathioprine and 6-mercaptopurine can induce and maintain longterm remission. Eur J Gastroenterol Hepatol. 2007; 19:865-869.

[13] Kandikattu HK, Venkateshaiah SU, Verma AK, Mishra A. Tacrolimus (FK506) treatment protects allergen- , IL-5- and IL-13- induced mucosal eosinophilia. Immunology. 2021; 163:220-235.

[14] Benjamin MR, Bochner BS, Peters AT. Mepolizumab use: Postapproval academic practice experience. Ann Allergy Asthma Immunol. 2018; 121:126-128.

[15] Straumann A, Conus S, Grzonka P, Kita H, Kephart G, Bussmann C, et al. Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: A randomised, placebocontrolled, double-blind trial. Gut. 2010; 59:21-30.

[16] Foroughi S, Foster B, Kim N, Bernardino LB, Scott LM, Hamilton RG, et al. Anti-IgE treatment of eosinophil-associated gastrointestinal disorders. J Allergy Clin Immunol. 2007; 120:594-601.

[17] Pinte L, Băicus C. Eosinophilic pancreatitis versus pancreatitis associated with eosinophilic gastroenteritis-A systematic review regarding clinical features and diagnosis. Rom J Intern Med. 2019; 57:284-295.

[18] Sunkara T, Rawla P, Yarlagadda KS, Gaduputi V. Eosinophilic gastroenteritis: Diagnosis and clinical perspectives. Clin Exp Gastroenterol. 2019; 12:239-253.

How to cite this paper

Eosinophilic Gastroenteritis Complicated with Intestinal Obstruction: A Case Report

How to cite this paper: Min Li. (2024) Eosinophilic Gastroenteritis Complicated with Intestinal Obstruction: A Case Report. International Journal of Clinical and Experimental Medicine Research8(3), 416-420.

DOI: http://dx.doi.org/10.26855/ijcemr.2024.07.008