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Image Guided Radiotherapy for Cervical Cancer: A Review

Date: June 24,2020 |Hits: 2087 Download PDF How to cite this paper

Rob A. Helms

University of Missouri-Kansas City, USA.

*Corresponding author: Rob A. Helms


Cervical cancer (CC) is one of the most common cancers in female worldwide. Radiotherapy plays an important role in the treatment of cervical cancer, and about 80% of CC patients need radiotherapy. However, many factors, including body position, body mass index and bladder filling state and so on, can affect the set-up errors during the treatment of radiotherapy. Recently, image guided radiotherapy has been widely used in clinic to reduce set-up errors and improve the accuracy of radiotherapy. Besides, image guided radiotherapy is applied for the analysis of cervical cancer target expansion. There is no doubt that radiotherapy could improve the therapeutic effect of cervical cancer, but the complications caused by radiotherapy should also draw our attentions.


[1]       Miyahira AK, Den RB, Carlo MI, et al. (2019). Tumor cell heterogeneity and resistance; report from the 2018 Coffey-Holden Prostate Cancer Academy Meeting [J]. The Prostate, 79(3): 244.

[2]       H. Shuang, J. Feng, C. Caineng. (2019). The value of radical radiotherapy in the primary tumor of newly diagnosed oligo-metastatic nasopharyngeal carcinoma patients [J]. Clinical & Translational Oncology, 21(2): 213-219.

[3]       Xinhe Liu, Ying Liu, Junning Wang. (2019). Mild Hyperthermia-Enhanced Enzyme-Mediated Tumor Cell Chemodynamic Therapy [J]. ACS Applied Materials & Interfaces, 11(26).

[4]       Mingyin Jiang, Linlin Wang, Jiaqi Gao. (2019). Risk Analysis of Radiotherapy Implementation Process Based on Failure Mode and Effect Analysis [J]. Chinese Journal of Medical Instrumentation, 43(3): 230-234.

[5]       Guo, CL (Guo Chuanling), Wang, JF (Wang Jufang), Jin, XD (Jin Xiaodong), et al. Studies on advantages of heavy ions in radiotherapy compared with gamma-rays [J]. Nuclear Inst & Methods in Physics Research B, 3923, 259(2): 997-1003.

[6]       Al Sajwani A., Sherlock M. (2019). Radiotherapy. In: Llahana S., Follin C., Yedinak C., Grossman A. (eds) Advanced Practice in Endocrinology Nursing. Springer, Cham.

[7]       Kate E. Burton. (2019). Radiotherapy[M]// Management of Adult Glioma in Nursing Practice.

[8]       Antoine Aspeel, Damien Dasnoy, Raphael M. Jungers. (2019). Optimal Intermittent Measurements for Tumor Tracking in X-ray Guided Radiotherapy[C]// Image-Guided Procedures, Robotic Interventions, and Modeling.

[9]       M. A. R. Loja, D. S. Craveiro, L. Vieira, et al. (2019). Radiotherapy-customized head immobilization masks: from modeling and analysis to 3D printing [J]. Nuclear Science and Techniques, 30(9).

[10]    Ma Shumei, Liang Zhenzhen, Chen Qiao. (2019). The challenges of precision radiotherapy technology to the traditional theory of radiobiology [J]. Chinese Journal of Radiological Medicine and Protection, 39(8): 563-571.

[11]    T Al-sudani, P Metcalfe, D Cutjar. (2019). Dose build up characteristics with eXaSkin bolus during 6MV radiotherapy: MOSkin dosimetry results [J]. Journal of Physics Conference Series, 1154(1): 012024.

[12]    MA Guangdong and HONG Li. (2018). Review of Imaging Radiotherapy for Cervical Cancer [J]. China Medical Devices, 33(5): 117-129.

[13]    Cao Fei, Zhao Yongliang, Li Ming, Liu Yu and Chu Kaiyue. (2019). Study on placement error and dosimetric difference of cervical cancer in supine and prone position [J]. Modern Oncology, 27(21): 3862-3865.

[14]    Mason J H. (2018). Quantitative cone-beam computed tomography reconstruction for radiotherapy planning [M].

[15]    Buckley J G, Wilkinson D, Malaroda A, et al. (2018). Investigation of the radiation dose from cone‐beam CT for image‐guided radiotherapy: A comparison of methodologies [J]. Journal of Applied Clinical Medical Physics, 19(1).

[16]    Chen Caixia, Liu Libin and Jiang Jie. (2019). The influence of cone beam CT image guidance on radiotherapy positioning error after breast conserving surgery [J]. Medical Equipment, 32(19): 30.

[17]    Yang H. J. (2019). Analysis of the accuracy of the positioning technique in radiotherapy of cervical cancer [J]. Cardiovascular Disease Electronic Journal of integrated traditional Chinese and Western Medicine, 7(16): 179-180.

[18]    Xu Hong, Chen Liang, Zhang Jing, Lu Guohua. (2010). Review of the development of radiotherapy simulation [J]. China Foreign Medical Treatment, 28: 190-191.

[19]    Leng Fu Lei. (2019). The comparative analysis of CBCT and EPID in radiotherapy of body tumor [J]. The Medical Journal of the Present Clinical, 32(02): 138.

[20]    Liu Bing, Zeng Zili, Wang Yongbing and Lin Feng. (2008). Study on the positioning error of cervical cancer in conventional radiotherapy by simulated positioning machine [J]. Medical Equipment, 22(1): 20-22.

[21]    Han Yuan-yuan, Mao Kai, Dai Tian-tian, et al. (2019). Dosimetric comparison between volume-modulated arc therapy and intensity modulated radiation therapy for cervical carcinoma in prone position [J]. Journal of China-Japan Friendship Hospital, 33(5): 277-280.

[22]    Xu Jian, Lin Hailong, Zou yunyun and Gong Wei. (2016). Analysis of the positioning errors of two kinds of fixators in intensity modulated radiotherapy for cervical cancer [J]. China Medical Device Information, 2016(12): 47-51.

[23]    Zhang Shengfeng, Wang Xuetao, Chen yancan, Zhou Hanfen, Yang Geng, Zhao Shiwu, Zhu Yuanhu and Cai Chunya. (2015). Study on the accuracy of positioning technique in radiotherapy of cervical cancer [J]. Clinical Medicine & Engineering, 22(3): 257-258.

[24]    Li Ping, Chen minbin, Tang Min, Jin Jun, Zhou Lina, Zhang Yan, Yang agile, Zhu Shengchao, Lu Jingjing and Tianye. (2019). Analysis of setup error by cone beam computed tomography in intensity modulated radiotherapy for cervical cancer [J]. Chinese Clinical Oncology, 24(5): 440-444.

[25]    Liu Yun, Yu Xian, Xiao He, Hu Nanand Wang Ge. (2016). Effect of body mass index on setup errors in cervical cancer treated with image-guided radiotherapy [J]. Journal of Third Military Medical University, 38(4).

[26]    Liu Yi, Dai Xinguo and Wang lisen. (2019). The influence of image guided radiotherapy on the positioning error of cervical cancer patients [J]. Henan Medical Research, 28(14): 2538-2540.

[27]    CAI Xuru, FANG Linming, JIN Cheng and CHEN Guofu. (2014). Study on effects of image guided techniques on setup error of cervical cancer in different body types [J]. China Modern Doctor, 52(33): 35-38.

[28]    Saara Kares, Olga Veijalainen, Ivana Kholová. (2019). HIGH RISK HPV testing as the primary screening method in an organised regional screening programme for cervical cancer: The value of HPV 16 and HPV 18 genotyping? [J]. Apmis, 2019.

[29]    Chen V E, Gillespie E F, Manger R P, et al. (2019). The impact of daily bladder filling on small bowel dose for intensity modulated radiation therapy for cervical cancer [J]. Medical Dosimetry, 44(2): 102-106.

[30]    Wipperman J, Neil T, Williams T. (2018). Cervical Cancer: Evaluation and Management [J]. 97(7): 449-454.

[31]    Bastien Rigaud, Antoine Simon, Maxime Gobeli. CBCT‐guided evolutive library for cervical adaptive IMRT [J]. Medical Physics, 2018, 45.

[32]    Lu Ying and Song Jianbo. (2016). Bladder volume changes and set-up error during the course of intensity-modulated radiation therapy of cervical cancer [J]. Journal of Practical Medical Techniques, 23(9): 942-944.

[33]    HE Ya, YANG Jin-ping, LIU Wei, et al. (2017). Investigation of fusion dose distribution for locally advanced cervical cancer under different bladder status with intensity-modulated radiotherapy combined with intracavitary brachytherapy [J]. Chinese Journal of Cancer Prevention & Treatment, 2017.

[34]    Caroline Lafond, Jairo Espinosa, Renaud de Crevoisier, et al. (2017). Quantification of dose uncertainties for the bladder in prostate cancer radiotherapy based on dominant eigenmodes [C]// 13th International Symposium on Medical Information Processing and Analysis.

[35]    H. Zhang, S. Lu, J. Lang. (2019). Analysis of Local Control Rate and Toxicity of Radiotherapy Dose of Cervical Cancer [J]. Practical Journal of Clinical Medicine.

[36]    Pobijakova M, Scepanovic D, Paluga M, et al. (2018). Dynamics of High Risk Clinical Target Volume reduction during Brachytherapy and impact on its coverage in patients with inoperable cervical cancer [J]. Neoplasma, 65(3): 425-430.

[37]    Nesseler J P, Charra-Brunaud C, Salleron J, et al. (2017). Effect of bladder distension on doses to organs at risk in Pulsed-Dose-Rate 3D image-guided adaptive brachytherapy for locally advanced cervical cancer [J].

[38]    Zhen X, Chen J, Zhong Z, et al. (2017). Deep convolutional neural network with transfer learning for rectum toxicity prediction in cervical cancer radiotherapy: a feasibility study [J]. Physics in Medicine & Biology, 62(21): S168.

[39]    Chakor Vora, Sudeep Gupta. (2019). Targeted therapy in cervical cancer [J]. ESMO Open, 2019, 3(Suppl 1).

[40]    Delgado A B, Cohen D, Eng T, et al. (2016). SU-F-T-590: Modeling PTV Dose Fall-Off for Cervical Cancer SBRT Treatment Planning Using VMAT and Step-And-Shoot IMRT [J]. 2016, 43(6): 3599-3599

[41]    Sun R, Mazeron R, Chargari C, et al. (2016). CTV to PTV in cervical cancer: From static margins to adaptive radiotherapy [J]. Cancer/Radiothérapie, 20(6-7): 622-628.

How to cite this paper

Image Guided Radiotherapy for Cervical Cancer: A Review

How to cite this paper: Rob A. Helms. (2020) Image Guided Radiotherapy for Cervical Cancer: A Review. International Journal of Clinical and Experimental Medicine Research, 4(3), 53-57.

DOI: http://dx.doi.org/10.26855/ijcemr.2020.07.004

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