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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2020.07.002

Molecular Mechanism of microRNA-155 in Connective Tissue Diseases

Jennifer L. Giguere *, Jessica A. Mabragana

College of Health and Human Sciences, Northern Illinois University, USA.

*Corresponding author: Jennifer L. Giguere

Published: June 24, 2020

Abstract

Abnormal expression of miRNAs is related to many diseases, including  immune cells rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, primary sjogren’s syndrome, and so on. Connective tissue diseases (CTDs) is a widely immune-mediated heterogeneous disease. The molecular mechanism of miRNA-155 in different CTDs is complex and changeable. In this paper, we systematically review the correlation between the miRNA-155 and CTDs, and demonstrated the molecular mechanism of miRNA-155 in connective tissue diseases. It might bring new potential markers for the  diagnosis and treatment.

Keyword

miRNA-155, connective tissue diseases, diagnosis, treatment

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How to cite this paper

Molecular Mechanism of microRNA-155 in Connective Tissue Diseases

How to cite this paper: Jennifer L. Giguere, Jessica A. Mabragana. (2020) Molecular Mechanism of microRNA-155 in Connective Tissue Diseases. International Journal of Clinical and Experimental Medicine Research, 4(3), 41-46.

DOI: http://dx.doi.org/10.26855/ijcemr.2020.07.002