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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
Frequency: bimonthly Email: ijcemr@hillpublisher.com
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2023.07.027

Effects of Thoracic Paravertebral Nerve Block Combined with PCIA on Hemodynamics and Stress in Patients Undergoing Radical Resection of Lung Cancer

Zhao Xu, Yikang Zhao, Bing Shan, Yaya Wang*

Department of Anesthesiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.

*Corresponding author: Yaya Wang

Published: August 21,2023

Abstract

Objective: To study and analyze the effects of thoracic paravertebral nerve block combined with patient controlled intravenous analgesia (PCIA) on hemodynamics and stress status of patients undergoing radical resection of lung cancer. Methods: A total of 100 patients treated with radical resection of lung cancer in our hospital from February 2021 to April 2023 were selected as the study objects, and were divided into study group and control group by random number table method, with 50 cases in each group. Both groups were given general anesthesia during radical resection of lung cancer. The control group was given intravenous controlled analgesia after surgery, and the study group was given thoracic paravertebral nerve block combined with intravenous controlled analgesia after surgery. The pain, hemodynamic level and stress response of the two groups were evaluated and compared at different stages. Results: VAS scores in the study group were lower than those in the control group at 2h, 6h, 24h and 48h after surgery, and the difference was statistically significant (P < 0.05). Immediately after surgery, there was no statistical difference in HR, CVP and other hemodynamic indexes between the two groups (P > 0.05). 24h after surgery, the levels of HR and CVP in the study group were lower than those in the control group, with statistical significance (P < 0.05). Stress response indexes such as cortisol and norepinephrine in the study group were lower than those in the control group at 1d, 3d and 5d after surgery, and the difference was statistically significant (P < 0.05). Conclusion: Thoracic paravertebral nerve block combined with PCIA can improve the early postoperative pain response, stabilize the hemodynamic level and improve the stress state in patients with lung cancer undergoing radical operation.

Keywords

Radical resection of lung cancer, Thoracic paravertebral nerve block, PCIA, Hemodynamics, Stress condition

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How to cite this paper

Effects of Thoracic Paravertebral Nerve Block Combined with PCIA on Hemodynamics and Stress in Patients Undergoing Radical Resection of Lung Cancer

How to cite this paper: Zhao Xu, Yikang Zhao, Bing Shan, Yaya Wang. (2023) Effects of Thoracic Paravertebral Nerve Block Combined with PCIA on Hemodynamics and Stress in Patients Undergoing Radical Resection of Lung Cancer. International Journal of Clinical and Experimental Medicine Research7(3), 452-456.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.07.027