References
[1] Fan J, Watanabe T. Atherosclerosis: Known and unknown [J]. Pathol Int, 2022, 72(3):151-160.
[2] Writing Committee of the Report. Key points of Report on Cardiovascular Health and Diseases in China 2020 [J]. Chinese Journal of Cardiovascular Research, 2021, 19(7):582-590.
[3] Report Group of Stroke Prevention. Brief report on stroke prevention and treatment in China 2020 [J]. Chinese Journal of Cerebrovascular Diseases, 2022, 19(2):136-144.
[4] Wang K, Wang R, Yang J, et al. Remnant cholesterol and atherosclerotic cardiovascular disease: Metabolism, mechanism, evidence, and treatment [J]. Front Cardiovasc Med, 2022, 9:913869.
[5] Zhang K, Qi X, Zhu F, et al. Remnant cholesterol is associated with cardiovascular mortality [J]. Front Cardiovasc Med, 2022, 9:984711.
[6] Masuda D, Yamashita S. Postprandial Hyperlipidemia and Remnant Lipoproteins [J]. J Atheroscler Thromb, 2017, 24(2): 95-109.
[7] Esan O, Wierzbicki A S. Triglycerides and cardiovascular disease [J]. Curr Opin Cardiol, 2021, 36(4):469-477.
[8] Burnett J R, Hooper A J, Hegele R A. Remnant Cholesterol and Atherosclerotic Cardiovascular Disease Risk [J]. J Am Coll Cardiol, 2020, 76(23):2736-2739.
[9] Nordestgaard B G, Varbo A. Triglycerides and cardiovascular disease [J]. Lancet, 2014, 384(9943):626-635.
[10] Sandesara P B, Virani S Sande Sara, Fazio S, et al. The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk [J]. Endocr Rev, 2019, 40(2):537-557.
[11] Varbo A, Nordestgaard B G. Directly measured vs. calculated remnant cholesterol identifies additional overlooked individuals in the general population at higher risk of myocardial infarction [J]. Eur Heart J, 2021, 42(47):4833-4843.
[12] Lupton J R, Faridi K F, Martin S Farida, et al. Deficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study [J]. J Clin Lipidol, 2016, 10(1):72-81.
[13] Rosenson R S, Davidson M H, Hirsh B J, et al. Genetics and causality of triglyceride-rich lipoproteins in atherosclerotic cardiovascular disease [J]. J Am Coll Cardiol, 2014, 64(23):2525-2540.
[14] Miller Y I, Choi S H, Fang L, et al. Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis [J]. Subcell Biochem, 2010, 51:229-251.
[15] Langsted A, Madsen C M, Nordestgaard B G. Contribution of remnant cholesterol to cardiovascular risk [J]. J Intern Med, 2020, 288(1):116-127.
[16] Alipour A, van Oostrom A J, Izraeljan A, et al. Leukocyte activation by triglyceride-rich lipoproteins [J]. Arterioscler Thromb Vasc Biol, 2008, 28(4):792-797.
[17] Ting H J, Stice J P, Schaff U Y, et al. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha [J]. Circ Res, 2007, 100(3):381-390.
[18] Varbo A, Benn M, Nordestgaard B G. Remnant cholesterol as a cause of ischemic heart disease: evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment [J]. Pharmacol Ther, 2014, 141(3):358-367.
[19] Saeed A, Feofanova E V, Yu B, et al. Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease [J]. J Am Coll Cardiol, 2018, 72(2):156-169.
[20] Hoogeveen R C, Ballantyne C M. Residual Cardiovascular Risk at Low LDL: Remnants, Lipoprotein (a), and Inflammation [J]. Clin Chem, 2021, 67(1):143-153.
[21] Varbo A, Benn M, Tybjaerg-Hansen A, et al. Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation [J]. Circulation, 2013, 128(12):1298-1309.
[22] Nakajima K, Nakano T, Tanaka A. The oxidative modification hypothesis of atherosclerosis: the comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma [J]. Clin Chim Acta, 2006, 367(1-2):36-47.
[23] Weitz J I, Fazio S. Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis [J]. Circ Res, 2019, 124(3):351-353.
[24] Ma H, Aziz K S, Huang R, et al. Arterial wall cholesterol content is a predictor of development and severity of arterial thrombosis [J]. J Thromb Thrombolysis, 2006, 22(1):5-11.
[25] Spasic I, Ubavic M, Sumarac Z, et al. Influence of lipid metabolism disorders on venous thrombosis risk [J]. J Med Biochem, 2021, 40(3):245-251.
[26] Trub A G, Wagner G R, Anderson K A, et al. Statin therapy inhibits fatty acid synthase via dynamic protein modifications [J]. Nat Commun, 2022, 13(1):2542.
[27] Ohmura H. Contribution of Remnant Cholesterol to Coronary Atherosclerosis [J]. J Atheroscler Thromb, 2022, 29(12):1706-1708.
[28] Castaner O, Pinto X, Subirana I, et al. Remnant Cholesterol, Not LDL Cholesterol, Is Associated with Incident Cardiovascular Disease [J]. J Am Coll Cardiol, 2020, 76(23):2712-2724.
[29] Do R, Willer C J, Schmidt E M, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease [J]. Nat Genet, 2013, 45(11):1345-1352.
[30] Varbo A, Nordestgaard B G. Remnant Cholesterol and Triglyceride-Rich Lipoproteins in Atherosclerosis Progression and Car-diovascular Disease [J]. Arterioscler Thromb Vasc Biol, 2016, 36(11):2133-2135.
[31] Elshazly M B, Mani P, Nissen S, et al. Remnant cholesterol, coronary atheroma progression and clinical events instatin-treated patients with coronary artery disease [J]. Eur J Prev Cardiol, 2020, 27(10):1091-1100.
[32] Levin M G. Remnant Lipoproteins as a Target for Atherosclerosis Risk Reduction [J]. Arterioscler Thromb Vasc Biol, 2021, 41(6):2076-2079.
[33] Kim J Y, Park J H, Jeong S W, et al. High levels of remnant lipoprotein cholesterol is a risk factor for large artery atherosclerotic stroke [J]. J Clin Neurol, 2011, 7(4):203-209.
[34] Varbo A, Nordestgaard B G. Remnant cholesterol and risk of ischemic stroke in 112,512 individuals from the general population [J]. Ann Neurol, 2019, 85(4):550-559.
[35] Li W, Huang Z, Fang W, et al. Remnant Cholesterol Variability and Incident Ischemic Stroke in the General Population [J]. Stroke, 2022, 53(6):1934-1941.