Xiaozhou Mao1,*, Leijing Ran1, Shutian Guo2
1School of Clinical Medicine, Dali University, Dali, Yunnan, China.
2Yuxi Jiangchuan District People's Hospital, Yuxi, Yunnan, China.
*Corresponding author: Xiaozhou Mao
Abstract
Objective: This study aims to analyze the levels of RDW in decompensated liver cirrhosis patients and further explore the influencing factors of death in decompensated liver cirrhosis patients. Methods: A single center retrospective analysis method was used in this study. 145 patients with decompensated cirrhosis admitted to the Second Affiliated Hospital of Dali University from March 2021 to March 2023 were selected as the research objects. According to the 30 day survival in the hospital, they were divided into survival group (n=116) and death group (n=29). The clinical data within 24 hours of admission in each group were recorded, including age, gender, RDW, ALT, AST, TBIL and γ- GGT and other laboratory examination indicators were recorded, while the MELD score of the study subjects at admission was recorded. Univariate binary logistic regression analysis was used to analyze the independent risk factors for death in decompensated liver cirrhosis patients. Results: In patients with decompensated liver cirrhosis death group RDW, MELD score, AST, TBIL is significantly higher than live group, differences were statistically significant (P < 0.05); ALT, γ-GGT is similar between the two groups has no statistical significance (P > 0.05). Single factor logistic regression analysis results showed that RDW, MELD score, TBIL is decompensation period the influence factors of prognosis of 30 day mortality in patients with liver cirrhosis. Conclusion: RDW has the advantages of convenient detection and low cost, and has good application prospects in evaluating the prognosis of decompensated liver cirrhosis patients in the future.
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