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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2023.07.004

Changes in Systolic Blood Pressure after Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension

Cheng Xue1, Yuting Wu2, Zheng Zhou2, Cui Chen2, Mao Liu1,*

1Department of Cardiology, Cardiovascular Research Center, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.

2School of Clinical Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.

*Corresponding author: Mao Liu

Published: August 7,2023

Abstract

The prevalence of hypertension (HTN) continues to increase in developing countries. The control rate of HTN is relatively low. The management of resistant HTN remains problematic. Recently, a promising new non-pharmacological technology using endovascular ultrasound renal denervation (uRDN) had shown its remarkable effect in resistant HTN patients. In this article, we pooled the currently available data concerning uRDN and conducted a meta-analysis to evaluate the efficacy of this technique systematically in patient with resistant HTN. Finally, a total of 3 studies out of 636 identified articles were retained. Compared to the blood pressure (BP) at randomization, the ambulatory systolic BP in daytime and nighttime reduced significantly after the procedure of uRDN. The reduction from baseline in 24-hour ambulatory systolic BP was 9.07 mm Hg. In conclusion, that uRDN was effective in reducing daytime and nighttime ambulatory systolic BP in resistant HTN populations. More randomized controlled trials with large scales and long-term follow-up are deserved in the future.

Keywords

Resistant hypertension, Ultrasound, Renal denervation, Ablation, Blood pressure

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How to cite this paper

Changes in Systolic Blood Pressure after Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension

How to cite this paper:  Cheng Xue, Yuting Wu, Zheng Zhou, Cui Chen, Mao Liu. (2023) Changes in Systolic Blood Pressure after Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension. International Journal of Clinical and Experimental Medicine Research7(3), 322-325.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.07.004