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International Journal of Clinical and Experimental Medicine Research

ISSN Print: 2575-7989 Downloads: 204318 Total View: 2406322
Frequency: quarterly ISSN Online: 2575-7970 CODEN: IJCEMH
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Article Open Access http://dx.doi.org/10.26855/ijcemr.2023.04.037

Comparison of Traditional Chinese Medicine with Trimebutine Maleate in the Treatment of Diarrhea-type Irritable Bowel Syndrome: A Meta-analysis

Mengyao Tan*, Yongju Wang, Qian Yang

Changchun University, Changchun, Jilin, China.

*Corresponding author: Mengyao Tan

Published: June 8,2023

Abstract

Objective: To compare the clinical efficacy of traditional Chinese medicine with trimebutine maleate in the treatment of diarrheal irritable bowel syndrome (liver stagnation and spleen deficiency type). Methods: The computer searched CNKI, Wangfang Data, VIP, Chinese Medical Database, web of science, PubMed, and The Cochrane Library for clinical randomized controlled trials of traditional Chinese medicine versus trimebutine maleate in the treatment of IBS-D, and analyzed the data with RevMan and Stata software. Results: A total of 20 RCTs with a total of 2,496 subjects were included, with 1,270 in the treatment group and 1,226 in the control group. The results of the meta-analysis revealed that traditional Chinese medicine outperforms trimebutine in terms of total effective rate of treatment, abdominal pain score, diarrhea score, bloating score, defecation satisfaction score, defecation frequency score, stool trait score, irritability, adverse reactions, and recurrence rate, and the difference is statistically significant (P<0.05). Conclusion: Traditional Chinese medicine has definite efficacy in the treatment of IBS-D, and the effect is superior to trimebutine maleate, making it suitable for clinical promotion and application.

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How to cite this paper

Comparison of Traditional Chinese Medicine with Trimebutine Maleate in the Treatment of Diarrhea-type Irritable Bowel Syndrome: A Meta-analysis

How to cite this paper:  Mengyao Tan, Yongju Wang, Qian Yang. (2023) Comparison of Traditional Chinese Medicine with Trimebutine Maleate in the Treatment of Diarrhea-type Irritable Bowel Syndrome: A Meta-analysis. International Journal of Clinical and Experimental Medicine Research7(2), 296-305.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.04.037